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ALOX12/12 Lipoxygenase Antibody

Applications

  • WB
  • ELISA

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Cow
Overview
Catalog # bs-3874R
Product Name ALOX12/12 Lipoxygenase Antibody
Applications WB, ELISA
Reactivity Human, Mouse
Predicted Reactivity Rat, Cow
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human 12 Lipoxygenase
Immunogen Range 101-200/663
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 239
Subcellular location Cytoplasm, Cell membrane
Synonyms 12 Lox; 12S lipoxygenase; 12S LOX; Alox 12; Alox12; Alox12L; Alox15; Arachidonate 12 lipoxygenase 12S type; Arachidonate 12 lipoxygenase; Arachidonate 12 lipoxygenase leukocyte type; Arachidonate 12 lipoxygenase, 12S type; Arachidonate 12 lipoxygenase, leukocyte type; EC1.13.11.31; LOG 12; LOG12; Platelet type 12 lipoxygenase; Platelet type lipoxygenase 12; P-12-LOX.
Background 12 Lipoxygenase is a non heme iron containing dioxygenase which stereospecifically incorporates molecular oxygen into cis,cis-1,4-pentadiene containing polyunsaturated fatty acids. Murine leukocyte 12 Lipoxygenase oxidizes arachidonic acid to 12(S)-HpETE and 15(S)-HpETE in a ratio of 3:1. Murine leukocyte 12 Lipoxygenase is a 75 kDa protein which is 58% homologous to murine platelet 12 Lipoxygenase, and 70% homologous to porcine leukocyte 12 Lipoxygenase.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000