HBEGF Polyclonal Antibody

Overview
Catalog #	bs-3576R
Product Name	HBEGF Polyclonal Antibody
Applications	ELISA, IHC-P, IF(ICC)
Reactivity	Human
Predicted Reactivity	Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human HB-EGF/DTSF
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	1839
Swiss Prot	Q99075
Subcellular location	Secreted, Cell membrane
Synonyms	DTR; DTS; DTSF; HEGFL; Proheparin-binding EGF-like growth factor; HBEGF
Background	Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Application Dilution
ELISA	1:500-1000
IHC-P	1:200-400
IF(ICC)	1:50-200