Phospho-Tyk2 (Tyr1054 + Tyr1055) Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-3437r-100uL |
| Product Name | Phospho-Tyk2 (Tyr1054 + Tyr1055) Polyclonal Antibody |
| Applications |
IHC-P
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Dog |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human Tyk2 around the phosphorylation site of Tyr1054/1055 |
| Modification Site | Tyr1054 + Tyr1055 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 7297 |
| Swiss Prot | P29597 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | TYK2Tyr1054/1055; Tyk2phospho Y1054/1055; TYK2 phospho Tyr1054/1055; p-TYK2 Tyr1054/1055; JTK 1; JTK1; TYK 2; Non receptor tyrosine protein kinase 2; Non receptor tyrosine protein kinase TYK2; Protein Tyrosine Kinase 2; Tyrosine kinase 2; TYK2_HUMAN; Non-receptor tyrosine-protein kinase TYK2. |
| Background | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]. |
| Application Dilution | |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is Phospho-Tyk2 (Tyr1054 + Tyr1055) Polyclonal Antibody (bs-3437R) validated for, and at what dilution?
bs-3437R is validated for IHC-P (1:200-400); IHC-F (1:100-500); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Phospho-Tyk2 (Tyr1054 + Tyr1055) Polyclonal Antibody (bs-3437R) react with?
Tested reactivity: Human, Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Dog.
How should bs-3437R be stored?
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Phospho-Tyk2 (Tyr1054 + Tyr1055) Polyclonal Antibody (bs-3437R)?
KLH conjugated synthetic phosphopeptide derived from human Tyk2 around the phosphorylation site of Tyr1054/1055