CYP2C9 Polyclonal Antibody

Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-CYP2C9 Polyclonal Antibody, Unconjugated (bs-2887R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Formalin-fixed and paraffin embedded rat liver labeled with Anti CYP2C9 Polyclonal Antibody, Unconjugated (bs-2887R) followed by conjugation to the secondary antibody

$Lane 1: Mouse Liver tissue lysates; Lane 2: Mouse Stomach tissue lysates probed with CYP2C9 Polyclonal Antibody, Unconjugated (bs-2887R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.$

Lane 1: Mouse Liver tissue lysates; Lane 2: Mouse Stomach tissue lysates probed with CYP2C9 Polyclonal Antibody, Unconjugated (bs-2887R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

WB
IHC-P
IHC-F
IF

Reactivity

Human
Mouse

Overview
Catalog #	bs-2887R
Product Name	CYP2C9 Polyclonal Antibody
Applications	WB, IHC-P, IHC-F, IF
Reactivity	Human, Mouse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human CYP2C9
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20C for 12 months.
Target
Gene ID	1559
Swiss Prot	P11712
Synonyms	CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9; Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase; CYP2C9
Background	Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan.
Application Dilution
WB	1:500-2000
IHC-P	1:100-500
IHC-F
IF