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IL-21 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Pig
Overview
Catalog # bs-2621R-A488
Product Name IL-21 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications WB, IF(IHC-P)
Reactivity Human, Mouse
Predicted Reactivity Rat, Dog, Cow, Pig
Specifications
Conjugation ALEXA FLUOR® 488
Host Rabbit
Source KLH conjugated synthetic peptide derived from human IL-21
Immunogen Range 65-155/155
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 59067
Swiss Prot Q9HBE4
Subcellular location Secreted
Synonyms Za11; IL-21; CVID11; Interleukin-21; IL21
Background Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200