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ICOS-L/B7-H2/CD275 Polyclonal Antibody

Applications

  • WB
  • ELISA
  • FCM

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
Overview
Catalog # bs-2471R
Product Name ICOS-L/B7-H2/CD275 Polyclonal Antibody
Applications WB, ELISA, FCM
Reactivity Human, Mouse
Predicted Reactivity Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from Rat ICOS-L
Immunogen Range 19-120/302
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 23308
Swiss Prot O75144
Subcellular location Cell membrane
Synonyms B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1; ICOSLG; KIAA0653
Background Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100