Cytochrome C Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-22900R |
| Product Name | Cytochrome C Polyclonal Antibody |
| Applications | WB, ELISA |
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Cow, Pig, Horse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Cytochrome c from bovine heart |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 54205 |
| Swiss Prot | P99999 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | CytC; CYC; CYCS; Cytochrome c somatic; HCS; CYC_HUMAN; CYC_MOUSE; Cytochrome-c; MSA06; THC4. |
| Background | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
| Application Dilution | |
| WB | |
| ELISA | 1:500-1000 |
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