PTGEs/Prostaglandin E Synthase Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1880R |
| Product Name | PTGEs/Prostaglandin E Synthase Polyclonal Antibody |
| Applications | WB, ELISA, IHC-P |
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, GuineaPig |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PTGEs |
| Clonality | Polyclonal |
| Clone # | #REF! |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 9536 |
| Swiss Prot | O14684 |
| Subcellular location | Cell membrane |
| Synonyms | PGES; MPGES; PIG12; PP102; PP1294; MGST-IV; MGST1L1; TP53I12; mPGES-1; MGST1-L1; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; p53-induced gene 12 protein; PTGES; MPGES1 |
| Background | Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
Powered by Bioz