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PTGEs Polyclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Pig
  • Guinea Pig
Overview
Catalog # bs-1880R
Product Name PTGEs Polyclonal Antibody
Applications WB, ELISA, IHC-P
Reactivity Human
Predicted Reactivity Mouse, Rat, Pig, Guinea Pig
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PTGEs
Immunogen Range 85-152/152
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 9536
Swiss Prot O14684
Subcellular location Cell membrane
Synonyms PGES; MPGES; PIG12; PP102; PP1294; MGST-IV; MGST1L1; TP53I12; mPGES-1; MGST1-L1; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; p53-induced gene 12 protein; PTGES; MPGES1
Background Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400