TFRC Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1782R-100uL |
| Product Name | TFRC Polyclonal Antibody |
| Applications |
ELISA
FCM
|
| Reactivity | Human, Mouse |
| Predicted Reactivity | Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Transferrin receptor |
| Immunogen Range | 21-120/760 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 7037 |
| Swiss Prot | P02786 |
| Subcellular location | Cell membrane |
| Synonyms | Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; TFRC |
| Background | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is TFRC Polyclonal Antibody (bs-1782R) validated for, and at what dilution?
bs-1782R is validated for ELISA (1:500-1000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TFRC Polyclonal Antibody (bs-1782R) react with?
Tested reactivity: Human, Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Rat.
How should bs-1782R be stored?
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise TFRC Polyclonal Antibody (bs-1782R)?
KLH conjugated synthetic peptide derived from human Transferrin receptor Immunogen range: 21-120/760.