phospho-JNK1 (Thr183) Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-17591r |
| Product Name | phospho-JNK1 (Thr183) Polyclonal Antibody |
| Applications |
WB
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthesised phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183 |
| Immunogen Range | 170-190/427 |
| Modification Site | Thr183 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 5599 |
| Swiss Prot | P45983 |
| Synonyms | JNK; JNK-46; JNK-55; JNK1; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK3; JNK3A; JNK3B1; JNK3B2; MAPK10; MAPK8; MAPK9; p493F12; p54a; p54aSAPK; p54bSAPK; PRKM10; PRKM8; PRKM9; SAPb; SAPK; SAPK(beta); SAPK1; SAPK1A; SAPK1B; SAPK1C; SAPKC; Serk2; JNK1 (phospho T183); p-JNK1 (phospho T183); AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JNK 1; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; mapk8; Mitogen activated protein kinase 8; Mitogen-activated protein kinase 8; MK08_HUMAN; p54 gamma; Prkm8; Protein kinase JNK1; Protein kinase, mitogen-activated, 8; SAPK 1; SAPK gamma; SAPK1; Stress-activated protein kinase 1; Stress-activated protein kinase JNK1; |
| Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jun 2013] |
| Application Dilution | |
| WB | |
| IHC-P | |
| IHC-F | |
| IF | |
Frequently asked questions
Which applications is phospho-JNK1 (Thr183) Polyclonal Antibody (bs-17591R) validated for, and at what dilution?
bs-17591R is validated for WB, IHC-P, IHC-F, IF.
Which species does phospho-JNK1 (Thr183) Polyclonal Antibody (bs-17591R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-17591R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise phospho-JNK1 (Thr183) Polyclonal Antibody (bs-17591R)?
KLH conjugated synthesised phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183 Immunogen range: 170-190/427.