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CCL21/6Ckine Polyclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-P
  • IF(IHC-P)

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-1666R
Product Name CCL21/6Ckine Polyclonal Antibody
Applications WB, ELISA, IHC-P, IF(IHC-P)
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Pig, Horse, Rabbit
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CCL21
Immunogen Range 24-134/134
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 6366
Swiss Prot O00585
Subcellular location Secreted
Synonyms ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21; C-C motif chemokine 21; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; Small-inducible cytokine A21; CCL21; UNQ784/PRO1600
Background Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200