Mannan Binding Lectin Polyclonal Antibody
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-1582R |
| Product Name | Mannan Binding Lectin Polyclonal Antibody |
| Applications |
ELISA
IHC-P
IHC-F
IF
|
| Predicted Reactivity | Human, Mouse, Rabbit |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Mannose-binding protein C |
| Immunogen Range | 31-130/248 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 4153 |
| Swiss Prot | P11226 |
| Subcellular location | Secreted |
| Synonyms | MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC; Mannose-binding protein C; Collectin-1; Mannan-binding protein; Mannose-binding lectin; MBL2 |
| Background | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
| IF | |