IL-23 Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1193R-100uL |
| Product Name | IL-23 Polyclonal Antibody |
| Applications |
WB
ELISA
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse |
| Predicted Reactivity | Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IL-23A |
| Immunogen Range | 101-196/196 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 51561 |
| Swiss Prot | Q9NPF7 |
| Subcellular location | Secreted |
| Synonyms | IL-23; IL-23A; IL23P19; P19; SGRF; IL23A_HUMAN; IL23A; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19 (IL-23p19); IL23A_MOUSE; IL23A_RAT; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; interleukin-six, G-CSF related factor |
| Background | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
| Application Dilution | |
| WB | 1:500-2000 |
| ELISA | 1:5000-10000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
| IF | |
Frequently asked questions
Which applications is IL-23 Polyclonal Antibody (bs-1193R) validated for, and at what dilution?
bs-1193R is validated for WB (1:500-2000); ELISA (1:5000-10000); IHC-P (1:200-400); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does IL-23 Polyclonal Antibody (bs-1193R) react with?
Tested reactivity: Human, Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Rat.
How should bs-1193R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise IL-23 Polyclonal Antibody (bs-1193R)?
KLH conjugated synthetic peptide derived from human IL-23A Immunogen range: 101-196/196.