phospho-IRS-2 (Ser731) Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-10998R-100uL |
| Product Name | phospho-IRS-2 (Ser731) Polyclonal Antibody |
| Applications |
ELISA
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated Synthesised phosphopeptide derived from human IRS-2 around the phosphorylation site of Ser731 |
| Modification Site | Ser731 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 8660 |
| Swiss Prot | Q9Y4H2 |
| Synonyms | IRS-2(phospho-Ser731); IRS-2(phospho S731); Insulin Receptor Substrate 2; IRS 2; IRS-2; IRS2; IRS2_HUMAN. |
| Background | The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. |
| Application Dilution | |
| ELISA | FCM |
| IHC-P | |
| IHC-F | |
| IF | |
Frequently asked questions
Which applications is phospho-IRS-2 (Ser731) Polyclonal Antibody (bs-10998R) validated for, and at what dilution?
bs-10998R is validated for FCM.
Which species does phospho-IRS-2 (Ser731) Polyclonal Antibody (bs-10998R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-10998R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise phospho-IRS-2 (Ser731) Polyclonal Antibody (bs-10998R)?
KLH conjugated Synthesised phosphopeptide derived from human IRS-2 around the phosphorylation site of Ser731