Recombinant human NT-proBNP protein, N-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-10879P |
| Product Name | Recombinant human NT-proBNP protein, N-His |
| Applications | ELISA |
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 4879 |
| Swiss Prot | P16860 |
| Background | Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76鈥揳mino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing. |
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