| Overview |
| bs-10757R-PE |
| GPM6A Polyclonal Antibody, PE Conjugated |
| WB, FCM |
| Mouse, Rat |
| Human, Dog, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GPM6A |
| 151-250/278 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 2823 |
| P51674 |
| Cell membrane |
| M6A; GPM6; Neuronal membrane glycoprotein M6-a; GPM6A |
| Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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