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CYP11A1 Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(IHC-P)

Reactivity

  • Rat
Overview
Catalog # bs-10099r
Product Name CYP11A1 Polyclonal Antibody
Applications WB, IHC-P, IF(IHC-P)
Reactivity Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 1583
Swiss Prot P05108
Subcellular location Mitochondrion, Membrane bound
Synonyms Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase side chain cleaving; Cholesterol side chain cleavage enzyme; CYP 11A; CYP11A; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450 11A1 mitochondrial; Cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450 subfamily XIA cholesterol side chain cleavage; Cytochrome P450 subfamily XIA; Cytochrome P450C11A1; P450scc; P450SCC; Steroid 20 22 lyase.
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
Application Dilution
WB
IHC-P
IF(IHC-P)