Angiotensin II Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-0587R-100uL |
| Product Name | Angiotensin II Polyclonal Antibody |
| Applications |
WB
IHC-P
IHC-F
IF
FLOW-CYT
|
| Specificity | The immunogen used generate this antibody is DRVYIHPF, corresponding to amino acids 34-41 of human Angiotensinogen. |
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | MAP conjugated synthetic peptide derived from human Angiotensin II |
| Immunogen Range | 34-41/485 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 183 |
| Subcellular location | Secreted |
| Synonyms | Alpha 1 antiproteinase, antitrypsin; Ang II; ANG III; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensinogen serpin peptidase inhibitor, clade A member 8; ANHU; Pre angiotensinogen; Serine or cysteine proteinase inhibitor; Serpin A8; SERPINA8; AT-2; AT-II; ANGT_HUMAN. |
| Background | Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets. |
| Application Dilution | |
| WB | IHC-P1:200-400 |
| IHC-P | IFIHC-P1:50-200 |
| IHC-F | |
| IF | |
| Flow-Cyt | |
Frequently asked questions
Which applications is Angiotensin II Polyclonal Antibody (bs-0587R) validated for, and at what dilution?
bs-0587R is validated for IHC-P (1:200-400); IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Angiotensin II Polyclonal Antibody (bs-0587R) react with?
Tested reactivity: Human.
How should bs-0587R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Angiotensin II Polyclonal Antibody (bs-0587R)?
MAP conjugated synthetic peptide derived from human Angiotensin II Immunogen range: 34-41/485.