| Overview |
| bsm-52797R |
| Glucocorticoid Receptor (1C1) Monoclonal Antibody |
| WB, FCM |
| Human, Mouse, Rat, Zebrafish |
| Specifications |
| Unconjugated |
| Rabbit |
| Human Glucocorticoid Receptor between 1 to 150 amino acids |
| Monoclonal |
| 1C1 |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
| Store at -20°C for 12 months. |
| Target |
| 2908 |
| P04150 |
| Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1, GR, NR3C1 |
| Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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