beta Arrestin 1 (3A11) Monoclonal Antibody

$Lane 1: PC12 cells; Lane 2: Jurkat cells; Probed with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Lane 1: PC12 cells; Lane 2: Jurkat cells; Probed with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

$IF(ICC) staining with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100 in A549 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.$

IF(ICC) staining with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100 in A549 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.

$IF(ICC) staining with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100 in PC-12 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.$

IF(ICC) staining with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100 in PC-12 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.

$Paraformaldehyde-fixed and paraffin-embedded Mouse lung tissue incubated with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.$

Paraformaldehyde-fixed and paraffin-embedded Mouse lung tissue incubated with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.

$Paraformaldehyde-fixed and paraffin-embedded Mouse brain tissue incubated with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.$

Paraformaldehyde-fixed and paraffin-embedded Mouse brain tissue incubated with beta Arrestin 1 (3A11) Monoclonal Antibody (bsm-52459R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.

Applications

WB
FCM
IHC-P
IF(ICC)
IHC

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-52459R
Product Name	beta Arrestin 1 (3A11) Monoclonal Antibody
Applications	WB, FCM, IHC-P, IF(ICC), IHC
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Human beta Arrestin 1 between 1 to 200 amino acids
Clonality	Monoclonal
Clone #	3A11
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	408
Swiss Prot	P49407
Synonyms	Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Background	The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Members of the_-Arrestin family regulate receptor binding to G proteins. _-Arrestins have been found to be located at postsynaptic sites, where they are thought to act in concert with_ARK (_ARK1, also designated GRK 2, or_ARK2, also designated GRK 3 to regulate G protein-coupled neurotransmitter receptors. Expression of_-Arrestin-1 and b-Arrestin-2 is seen predominantly in spleen and neuronal tissues. It has been shown that_-Arrestin-1 expression is modulated by intracellular cAMP, which may be a novel mechanism for the regulation of receptor-mediated responses.
Application Dilution
WB	1:300-5000
FCM	1:20-100
IHC-P	1:200-400
IF(ICC)	1:50-200
IHC

Applications

Reactivity

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