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Thrombomodulin (3G7) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-54333R
Product Name Thrombomodulin (3G7) Monoclonal Antibody
Applications WB, IHC-P, IF(ICC)
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein corresponding to the C-terminus of human Thrombomodulin
Clonality Monoclonal
Clone # 3G7
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID 7056
Swiss Prot P07204
Subcellular location Cell membrane
Synonyms Thrombomodulin; Fetomodulin; CD141; TM; THBD; THRM; AHUS6; BDCA3; THPH12
Background Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200