(+)-Aphidicolin
| Overview | |
| Catalog # | bs-75735C |
| Product Name | (+)-Aphidicolin |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 1 year after receipt when stored at +4°C. After reconstitution protect from light at -20°C. |
| Target | |
| Product Information | CAS Number: 38966-21-1 Molecular formula: C20H34O4 Molecular weight: 338.5 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (50 mg/ml), methanol (10 mg/ml) or 100% ethanol; insoluble in water. InChiKey: NOFOAYPPHIUXJR-APNQCZIXSA-N SMILES: [H][C@]12C[C@@H]3C[C@]1(CC[C@]3(O)CO)[C@@]1(C)CC[C@@H](O)[C@@](C)(CO)[C@]1([H])CC2 |
| Description | Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Antileishmanial agent. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA methylation/demethylation modulator. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer. |
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