(R)-FSL-1
| Overview | |
| Catalog # | bs-75296C |
| Product Name | (R)-FSL-1 |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: n.d. Molecular formula: C84H140N14O18S Molecular weight: 1666.2 Purity: Absence of detectable protein or DNA contaminants with agonistic TLR activity. Appearance: Colorless powder. Solubility: Soluble in water (10mg/ml). Use a homogeniser or sonicator to prepare a homogenous solution. InChiKey: VJJLLNHELGKSNA-QWIIDARVSA-N SMILES: [H][C@@](COC(=O)CCCCCCCCCCCCCCC)(CSC[C@]([H])(N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O)OC(=O)CCCCCCCCCCCCCCC |
| Description | R-FSL-1 (R-Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of the 44kDa lipoprotein LP44 of Mycoplasma salivarium [1]. The naturally occurring R-stereoisomer is biologically more active than the S-stereoisomer [4]. Stimulator of TLR2/TLR6 [2-13]. Inducer of TNF-alpha production in macrophages [5]. Upregulates proinflammatory cytokines [3,5]. Activator of the proinflammatory transcription factor NF-kappaB [3]. |
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